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SYNTHESIS

CPI Georgia Department of Synthesis deals with the production of substances, enriched with O‑18, O‑17, N‑15 isotopes for medicine, science and technology.

Water enriched with O‑18 higher, than 98 at. %, used for PET diagnostics is one of the main products, manufactured at the Department.

Water, enriched with O‑17 higher than 90 % has become of special interest lately, as it provides a unique possibility for its wide application in medical diagnostics by the method of NMR tomography.

Salts, enriched with N‑15 (99 %), are also important labeled compounds, produced for further synthesis of complex labeled organic compounds.

Developed synthesis technologies exclude any side reactions, which provides high purity of obtained labeled compounds and minimum isotope losses. All the stages of synthesis proceed in closed‑loop systems, which eliminates possibility of isotope dilution and contamination of highly enriched products with components, penetrating from the external environment.

Flow diagram of the production process sequences looks as follows:

15N18O.png
15N17O.png
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